Research Articles
The Spiro-Intermediate: Unveiling Nature's Secret to Building the Pigments of Life
Discover how 2H-pyrroles and the mysterious spiro-intermediate unlock the secrets of porphyrin biosynthesis, the pigments essential to life on Earth.
The Digital Treasure Hunt for Tomorrow's Medicines
How scientists are using genetic blueprints to uncover nature's hidden healing compounds through genome mining and biosynthesis research.
Nature's Molecular Assembly Lines: The Fascinating Machinery Behind Polyketide Antibiotics
Explore the fascinating biosynthesis of polyketide antibiotics, nature's molecular assembly lines that produce life-saving medicines.
Nature's Chemists: How Heinz Floss and Christopher Walsh Decoded Life's Molecular Mysteries
Explore the groundbreaking work of Heinz Floss and Christopher Walsh in natural product chemical biology and their contributions to understanding antibiotic resistance.
The Great Molecular Snip: How Cells Use Custom Scissors to Build the Stuff of Life
Discover how cells use diverse enzymatic strategies to cleave propionate side chains in tetrapyrrole biosynthesis, a crucial process for life.
The Hidden Geometry of Life: How Molecular Handedness Shapes Nature's Medicines
Exploring how pikromycin synthase controls molecular handedness in polyketide biosynthesis and its implications for drug development.
Scaling the Molecular Mountains: How Chemists and Enzymes Build Nature's Most Complex Molecules
Exploring the integration of chemical synthesis and biosynthesis strategies in creating complex natural products for drug discovery
Nature's Assembly Lines: Rewiring Microbe Factories to Build Next-Gen Cancer Medicines
Exploring how soil-dwelling bacteria and combinatorial biosynthesis are revolutionizing cancer medicine through epothilone engineering.
The Alchemy Within: How Plants Craft Complex Medicines and How Science is Supercharging Nature's Factories
Exploring how plants produce medicinal alkaloids and how genetic engineering is revolutionizing their production through biotechnology.
The Hidden Alchemists: Metabolic Engineering's Quest to Brew Quinic Acid
Explore how metabolic engineering is revolutionizing quinic acid production through microbial factories, enzyme fusion breakthroughs, and sustainable biotechnology.