Research Articles
BioNavi-NP vs RetroPath2.0: Which Pathway Prediction Tool Delivers Superior Performance for Drug Discovery?
This article provides a comprehensive performance comparison between two leading computational tools for biosynthetic pathway prediction, BioNavi-NP and RetroPath2.0.
BioNavi-NP vs. Rule-Based Approaches: A Comprehensive Accuracy Analysis for Bio-Retrosynthesis in Drug Discovery
This article provides a detailed comparative analysis of BioNavi-NP, a state-of-the-art neural planning framework, against traditional rule-based approaches for bio-retrosynthesis in natural product synthesis.
BioNavi-NP Tutorial: A Complete Guide to AI-Powered Natural Product Pathway Design for Drug Discovery
This comprehensive tutorial provides researchers and drug development professionals with a step-by-step guide to BioNavi-NP, a groundbreaking AI platform for designing biosynthetic pathways of complex natural products.
BioCAT: The Complete Guide to Nonribosomal Peptide Producer Identification for Drug Discovery
This guide provides researchers, scientists, and drug development professionals with a comprehensive overview of the BioCAT (Biosynthetic Gene Cluster Analysis Tool) for identifying microbial producers of nonribosomal peptides (NRPs).
Biogenic vs. Chemical Palladium Nanoparticles: A Comparative Analysis of Catalytic Performance for Biomedical Applications
This article provides a comprehensive comparison of the catalytic performance of biogenically synthesized (Bio-PdNPs) and chemically synthesized (Chem-PdNPs) palladium nanoparticles.
BiG-SCAPE Guide: Network Analysis of Biosynthetic Gene Clusters for Drug Discovery
This comprehensive guide provides researchers, scientists, and drug development professionals with a deep dive into BiG-SCAPE, the premier tool for analyzing Biosynthetic Gene Cluster (BGC) Families.
From Soil to Drug: A Comprehensive Guide to BGC Detection in Metagenomic Assemblies
This article provides a comprehensive overview of the current state, methods, and challenges in detecting Biosynthetic Gene Clusters (BGCs) within metagenomic assemblies.
BGC Boundary Determination: A Practical Guide to Synteny Analysis for Natural Product Discovery
This article provides a comprehensive guide for researchers and drug development professionals on utilizing synteny analysis for precise Biosynthetic Gene Cluster (BGC) boundary determination.
B-Factor Analysis vs Molecular Dynamics: Choosing the Right Tool for Protein Flexibility in Drug Discovery
This article provides a comprehensive comparison of B-factor (temperature factor) analysis from crystallographic data and Molecular Dynamics (MD) simulations for predicting protein flexibility—a critical parameter in structural biology and drug...
B-Factor Analysis Explained: A Complete Guide to Identifying Flexible Protein Regions for Drug Discovery
This comprehensive guide details B-factor (temperature factor) analysis as a critical tool in structural biology for quantifying protein flexibility from X-ray crystallography and cryo-EM data.