Research Articles
CRISPR/Cas9 RNP for Gene Cluster Validation in Fungi: A Practical Guide for Natural Product Discovery
This article provides a comprehensive resource for researchers utilizing CRISPR/Cas9 ribonucleoprotein (RNP) complexes to validate biosynthetic gene clusters (BGCs) in fungi.
CRISPR-Cas Genome Editing: Revolutionizing Plant Metabolic Engineering for Pharmaceutical Production
This article provides a comprehensive overview of CRISPR-Cas-based genome editing for engineering plant metabolic pathways, tailored for researchers, scientists, and drug development professionals.
Engineering Nature's Pharmacy: CRISPR Editing of Terpene Pathways for Next-Gen Therapeutics
This article provides a comprehensive guide for researchers and drug development professionals on the application of CRISPR-Cas systems to engineer terpene biosynthetic pathways.
Harnessing CRISPR: A Guide to Editing PKS Gene Clusters for Next-Gen Drug Discovery
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on utilizing CRISPR-Cas systems to edit polyketide synthase (PKS) gene clusters.
Accelerating Enzyme Engineering: A Guide to CRISPR-Cas Directed Evolution for Drug Discovery
This article provides a comprehensive guide for researchers on harnessing CRISPR-Cas systems for directed evolution of enzymes.
CRISPR-Guided Evolution: Accelerating Protein Engineering and Drug Discovery
This article provides a comprehensive guide for researchers on CRISPR-Cas mediated directed evolution, a transformative methodology for accelerating protein engineering.
Harnessing CFD Simulation to Optimize Bioreactor Gradients for Advanced Cell Culture and Bioprocessing
This article provides a comprehensive guide to Computational Fluid Dynamics (CFD) simulation for analyzing and optimizing gradients in bioreactors.
CAGECAT Tutorial: A Step-by-Step Guide to Comparative Gene Cluster Analysis for Drug Discovery
This comprehensive tutorial provides researchers, scientists, and drug development professionals with essential knowledge and practical guidance for using CAGECAT, a powerful tool for comparative gene cluster analysis.
Biosynfoni Fingerprinting: A Computational Toolkit for Biosynthetic Gene Cluster Similarity Analysis and Drug Discovery
This article provides a comprehensive guide to the Biosynfoni framework, a specialized Python toolkit for generating molecular fingerprints from Biosynthetic Gene Clusters (BGCs).
BioNavi-NP vs RetroPath2.0: Which Pathway Prediction Tool Delivers Superior Performance for Drug Discovery?
This article provides a comprehensive performance comparison between two leading computational tools for biosynthetic pathway prediction, BioNavi-NP and RetroPath2.0.