Research Articles
The Green Killers' New Gambit: Disarming Weeds by Starving Them of Genetic Building Blocks
Discover how a novel herbicide mechanism disrupts pyrimidine biosynthesis, offering a new strategy against herbicide-resistant superweeds.
Forged in Fire: The Strained World of the Cyclopropane Ring
How chemists are harnessing cationic power to build nature's most tense molecular scaffold through biosynthetic inspirations
Aphidicolin: The Fungus's Secret Weapon That Paused Cell Biology
Explore the fascinating chemistry and biosynthesis of Aphidicolin, a natural compound that revolutionized cell biology research by pausing DNA replication.
The Natural Alchemists: How Soil Microbes Craft Life-Saving Antibiotics
Discover how soil microorganisms biosynthesize sisomicin and gentamicin, the clinically valuable aminoglycoside antibiotics, through complex enzymatic pathways.
Unlocking the Body's Arsenal: The Tiny Molecule That Revs Up Your Immune System
Discover how 1-(2-Methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridine-4-amine stimulates cytokine biosynthesis to enhance immune response
The Flash of Genius: A Glowing Clue to the Penicillin Puzzle
Discover how fluorescamine and a critical sidekick molecule helped scientists crack the code of penicillin's biosynthesis through brilliant chemistry.
Nature's Blueprint: The Fascinating Biosynthesis of Ergot Alkaloids
Explore the dual nature of ergot alkaloids as toxins and medicines, their unique ergoline ring structure, and the groundbreaking discovery of the EasC enzyme's superoxide mechanism.
Unlocking Nature's Medicine Cabinet: The Final Piece in the Iridoid Puzzle
Discover the groundbreaking discovery of iridoid cyclase, the missing piece in iridoid biosynthesis, and its implications for sustainable drug production.
The Secret Alchemy of Alfalfa: How a Common Plant Brews Medicine
Discover how Medicago species like alfalfa produce potent natural compounds through sophisticated biosynthesis pathways
Unlocking Nature's Protein Factory: The Wheat Germ Cell-Free System
Explore how sequence-based analyses revealed biosynthesis rate limiting factors in wheat germ cell-free systems and revolutionized protein production.