Research Articles
The Bacterial Wall Breakers: Crafting a Next-Gen Antibiotic from a Molecular Scaffold
Explore how scientists are optimizing the benzothiazole indolene scaffold to create next-generation antibiotics targeting bacterial cell wall assembly.
The Master Key: Forging a New Weapon in the War Against Superbugs
Discover how Indole Naphthyridinones are revolutionizing antibiotic development by targeting bacterial fatty acid synthesis through dual inhibition of FabI and FabK enzymes.
Taming Cellular Factories: The New Blueprint for Life-Saving Antibiotics
Discover how scientists are using biomimetic synthesis to create next-generation antibiotics by harnessing cytochrome P450 enzymes and microbial engineering.
The Natural Alchemists: How Soil Microbes Craft Life-Saving Antibiotics
Discover how soil microorganisms biosynthesize sisomicin and gentamicin, the clinically valuable aminoglycoside antibiotics, through complex enzymatic pathways.
The AI Revolution: How Second-Generation Antibiotics Are Winning the War Against Superbugs
Discover how second-generation antibiotics and AI-driven approaches are revolutionizing the fight against drug-resistant superbugs.
Unidos no Combate: The Strategic Alliance between Clavulanic Acid and Cephamycin C in the War against Superbugs
Exploring the biosynthesis, isolation processes, and mechanism of action of clavulanic acid and cephamycin C in combating antibiotic resistance.
Deep-Sea Drug Hunt: The Microbial Arms Race in Earth's Final Frontier
Exploring how deep-sea microbes could provide solutions to the antibiotic resistance crisis through novel compounds and mechanisms.