Research Articles
The Cellular Factory: Harnessing Nature's Molecular Machines
Explore how enzyme-containing cells and extracts are revolutionizing science, from lab benches to life-saving therapies.
The Oxygen Gatekeepers: How Enzymes Tame a Reactive Gas for Cellular Chemistry
Discover how enzymes control oxygen binding and functionalization of the flavin cofactor through precise molecular mechanisms.
The Silent Symphony of Life: How Enzymes Rule Everything
Explore the fascinating world of enzymes, enzyme mechanisms, proteins, and the surprising role of nitric oxide in cellular signaling and regulation.
Nature's Minimalist Iron Masterpiece: The 2-His-1-Carboxylate Facial Triad
Exploring the elegant 2-His-1-carboxylate facial triad - nature's minimalist design enabling remarkable chemical transformations in mononuclear non-heme iron enzymes.
Nature's Tiny Pharmacists: The Hunt for New Microbial Drug Factories
How scientists are uncovering hidden enzymes to build the next generation of life-saving medicines from microorganisms.
Unlocking Cures: How Enzyme-Targeting Drugs Are Revolutionizing Medicine
Explore how enzyme-targeted drug design is creating revolutionary treatments for diseases like MASH, sepsis, and more through precision medicine approaches.
The Great Molecular Snip: How Cells Use Custom Scissors to Build the Stuff of Life
Discover how cells use diverse enzymatic strategies to cleave propionate side chains in tetrapyrrole biosynthesis, a crucial process for life.
The Radical Artisans Inside Your Cells: How Unseen Enzymes Craft Molecular Wonders
Exploring the extraordinary capabilities of Radical S-adenosylmethionine (SAM) enzymes in constructing essential sulfur-containing molecules for life.
The Hidden Cyclists Inside Microbes: How Enzymes Perform Molecular Magic to Build Antibiotics
Discover how specialized enzymes perform [4+2] aza-cycloaddition reactions to build life-saving thiopeptide antibiotics, revealed through structural biology breakthroughs.
The Atomic Architects of Life: Decoding Nature's Fastest Enzymes
Exploring the atomic mechanisms behind nature's most efficient enzymes - OMPD and CaAAD - through cutting-edge imaging and computational modeling.