Research Articles
Nature's Molecular Masterpieces: The Double-Agent Diterpenoids Fighting Disease
Explore the fascinating world of naturally occurring diterpenoid dimers - complex molecular structures with remarkable medicinal properties against cancer and antibiotic-resistant bacteria.
The Digital Treasure Hunt for Nature's Miracles: A Cautionary Tale
How computers promised a new golden age of drug discovery, and why scientists had to go back to the lab.
Nature's Alchemists: The Secret Code for Building Molecular Masterpieces
Discover how nature builds complex molecules with isonitriles and alkynes through sophisticated biosynthetic pathways
Nature's Hidden Blueprints: Solving Peptide Puzzles Through Chemical Synthesis
Explore how chemical synthesis unravels the mysteries of peptidic natural products like surugamides and thioamycolamides, revealing nature's biosynthetic pathways.
Nature's Molecular Origami: The Art of Oxidative Cyclization
Explore how oxidative cyclization transforms simple molecular chains into complex natural products with medicinal properties like antibiotics and cancer treatments.
The Guanidine Gambit: Nature's Potent Molecular Masterpiece
Explore the fascinating world of guanidine natural products - from spider venoms to life-saving drugs. Discover the chemistry and biology behind these powerful molecules.
Digital Alchemy: How Computers Are Unlocking Nature's Secret Recipes
Explore how computational chemistry is revolutionizing our understanding of natural product biosynthesis and drug discovery.
Nature's Molecular Assembly Lines: The Fascinating World of Polyketide Synthesis
Explore the remarkable world of polyketide biosynthesis - nature's molecular assembly lines that produce vital medicines including antibiotics, anticancer drugs, and cholesterol medications.
DeepRiPP: How AI Is Revolutionizing the Hunt for Nature's Hidden Medicines
Discover how DeepRiPP uses AI and multiomics data to automate the discovery of novel ribosomally synthesized natural products with therapeutic potential.
Microbial Alchemists: The Fascinating Biosynthesis of Natural Bipyridine Compounds
Discover how microorganisms synthesize complex bipyridine compounds through an unusual hybrid PKS-NRPS biosynthetic pathway.