Research Articles
The Hidden Factory: How Tiny Molecules Power Our World
Explore the fascinating biosynthesis of iso-chorismate-derived quinones - the molecular machines powering life from bacteria to plants.
M. Daniel Lane: Decoding the Biochemistry of Appetite and Obesity
Explore the scientific legacy of M. Daniel Lane, whose groundbreaking research on biotin enzymes, adipogenesis, and hypothalamic appetite control transformed our understanding of metabolism and obesity.
Seeing the Invisible: How a Chemistry Trick Is Illuminating Cancer's Secrets
Scientists harness transfer hydrogenation to light up formate in living cells, opening new windows into cancer metabolism and disease diagnostics.
Porphyrins and Porphyrinogens: Unveiling Heme's Hidden Cycle in Rabbits
Explore the fascinating metabolism of porphyrins and porphyrinogens in rabbits through intravenous injection experiments and their implications for human health.
The Body's Chemical Backfire: When Life-Saving Drugs Turn Toxic
Exploring biological reactive intermediates - the dangerous molecules created when our bodies process drugs and chemicals, and how this research improves human safety.
The Invisible Storm: How 'Forever Chemicals' Hijack a Water Flea's Metabolism
Discover how PFAS forever chemicals disrupt aquatic ecosystems through metabolic changes in Daphnia magna at sublethal exposure levels.
Hitler's Gift and the Era of Biosynthesis
Explore how scientific exodus during WWII revolutionized biosynthesis research and led to groundbreaking discoveries in metabolic pathways and enzyme functions.
The Spark of Life: How a Simple Molecule Could Have Powered Early Evolution
Exploring how thioesters could have acted as primordial batteries to power the first metabolic networks before enzymes existed.
Bile Acids: From Digestion to Doctors—How These Tiny Molecules Revolutionized Medicine
Explore the fascinating journey of bile acids from simple digestive aids to sophisticated signaling molecules that regulate health and disease.
Isotopic Memory: How Atoms Remember Your Metabolic Past
Discover how stable isotopes create atomic records of metabolic history, revealing insights from ancient climates to cancer research through isotopic remembrance.