Research Articles
The Muraymycin Marvel: Nature's Blueprint for Next-Generation Antibiotics
Explore the fascinating science behind muraymycins, how chemists recreate nature's designs in the laboratory, and develop them into potential medicines against drug-resistant pathogens.
Nature's Molecular Assembly Lines: The Fascinating Machinery Behind Polyketide Antibiotics
Explore the fascinating biosynthesis of polyketide antibiotics, nature's molecular assembly lines that produce life-saving medicines.
Nature's Chemists: How Heinz Floss and Christopher Walsh Decoded Life's Molecular Mysteries
Explore the groundbreaking work of Heinz Floss and Christopher Walsh in natural product chemical biology and their contributions to understanding antibiotic resistance.
Hidden Choreography: How a Bacterial Enzyme's Dance Holds Keys to New Antibiotics
Exploring the molecular mechanisms of A. baumannii's ATP phosphoribosyltransferase and its potential as an antibiotic target
The Alchemy of Survival: How Fungi Forge Penicillins and Cephalosporins
Explore the fascinating biochemistry behind penicillin and cephalosporin production in fungi and bacteria, and how these antibiotics revolutionized medicine.
The Hidden Cyclists Inside Microbes: How Enzymes Perform Molecular Magic to Build Antibiotics
Discover how specialized enzymes perform [4+2] aza-cycloaddition reactions to build life-saving thiopeptide antibiotics, revealed through structural biology breakthroughs.