Research Articles
Structural Secrets: How Scientists Are Disarming a Superbug's Molecular Machinery
Discover how researchers are using structural biology to target IspC enzyme in Acinetobacter baumannii for developing new antibiotics against drug-resistant superbugs.
How a Bacterial Enzyme Outsmarts Drug Resistance
Discover how the PLP-dependent enzyme GenB3 catalyzes C-3',4'-dideoxygenation in gentamicin biosynthesis, enabling bacteria to evade drug resistance mechanisms.
The Polyyne Puzzle: How Evolutionary Trees Led to a Novel Antibacterial Compound
Discover how phylogeny-guided genome mining revealed protegencin, a novel antibacterial compound with potential applications in medicine and agriculture.
Tiny Fungal Factories: How a Common Mold is Brewing Tomorrow's Antibiotics
Discover how Fusarium oxysporum fungus produces silver nanoparticles to combat drug-resistant superbugs like KPC and ESBL bacteria.
Showdomycin: The Molecular Spy That Infiltrates Bacteria's Secret Weapon Factory
Discover how showdomycin, a natural compound, is revolutionizing bacterial enzyme detection and fighting antibiotic resistance through advanced chemical probing techniques.
How Bacterial Iron-Sulfur Clusters Unlock Aminoglycoside Antibiotic Uptake
Discover how iron-sulfur cluster biosynthesis controls aminoglycoside uptake through proton motive force, challenging the ROS hypothesis in antibiotic action.